Man... A lot of Indiana guys on this thread!
Encore Billy... You should try some big bullets. 
I shoot a 450 grain solid, flat nose in a sabot.  I have shot 16 deer in 3 years with them (including a couple clean ups for guys that had deer wounded) and they are flat out awesome.  I was shooting full size 600 grain solids before that.
My last doe was around 150 yards.  Even with a 450 grain flat nose!
Jabba