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I have shot and owned a Rem 700 - 280 for about 20 years. I have shot just about everything that walks in New England including bear, moose and deer. I would have not problem taking everything except the big bears with it. With that being said I would feel the same for a good 270.
I chose the 280 because I hand load just about everything I shoot. I like the 140 Nosler for med game pluse for Moose and Bear I shoot the 160 gr Nosler Partition.
If I was to ever hunt Elk I would use the 160.
Again really ain't much difference between the two.
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