Hey Brit,
as the others mentioned there is really no noticable difference in the .243 and the 6mm remington. On paper there is, but in the field you can't tell the difference.
I've been told, that "in general" the .243 handles the lighter bullets better and the 6mm handles the heavier bullets better, but i'd take that with a grain of salt, since my .243 seems to handle both quite well, it can shoot better than i can with either.
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