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Most of the "standard" factory loads for the 45 Colt are very mild - they have to be loaded down until they're still safe in revolvers made 130 years ago.
You can buy special hot loads intended for guns made yesterday, but they're probably spendy.
Super-magnum loads like the 454 Casull, 475 Linebaugh, 480 Ruger and the new 500 S&W are massively powerful at both ends. There's simply no way to compare them to even the hottest 357 ammo...unless you can compare a 105 howitzer to a Garand.
M70, if a 357 is the heaviest handgun you've yet owned, may I respectfully suggest that you not even think about a super-magnum for quite some time? I repeat the "respectfully."
A good 44 (as I posted above) is probbaly all the gun you'll ever need, and possibly all you'll ever shoot comfortably. I'd work up to full 44 Mag performance, in fact. Begin with 44 Special loads (which are delightful). The first round of 44 Mag you touch off is gonna be an eye-opener. They recoil about four to six times what a 357 does.
A super mag? They kick several times more than a 44!!
There are gazillions of 44s out there. See if you can borrow one, rent one or just try one the next time you're at the range. Then you'll know.
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