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There are several suppliers of heavy-duty loads in 45 Colt: Core-Bon, Buffalo Bore and others pop to mind.
Almost everybody makes suitable 44 Mag loads, and if you really like punishment, there's always the 454 Casull, 480 Ruger or even (God forbid) the 500 S&W. NONE of them is wimpy.
Nor would I think twice if I had a 10mm Auto in my holster, for that matter.
Just stay away from hollowpoints in any round you choose - they don't penetrate as well as softpoints or hard-cast lead, and bears need penetration to reach the vitals.
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