I have the three calibers you suggest and they are great. I also have 18 other calibers from 22-250 to 7mm mag and 30-06. If for some reason I had to sell all except one, I'd keep the 30-06. Talk about any caliber you want and I agree they all have their following, but the 30-06 shines the brightest. If for any reason on a trip you forgot or need ammo any back country store or city K-Mart store that sells ammo will have something you can shoot. And you can shoot anything in North America with it. Thank God and a Vet. I can own all the rifles I want. If it's only one, my vote goes to the reliable 30-06. Period.