Pretty cool Skeet and Larryjk shoot 35 Whelens. I shoot a 350 RM which has the same ballistics. I've only had it for about 2 years but it's now my main elk rifle. I don't feel much more recoil than a 30-06. I had debated on the .338 mag and the .300 WM for elk. IMO the .300s are great for long distance elk rifles and the .338 WM is definitely a great elk rifle with a little bit better ballistics than the .350 RM. But after reading about the mild recoil, etc. I settled on the 350. I'm very happy with it. I feel I can take anything in NA with it with the possible exception of the really big bears (brown/polar). I was discussing the .350 with the Africa guy when he brought up the .375 H&H. If I ever get over there, I would likely be hunting only plains game and would love to take the .350, but I'd have to be able to ship ammo or carry it with me.
And if I ever get a bigger rifle for Africa or the really big bears, it would likely be the .375. And I would want a heavy one as you all suggested.
Mike