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They do work. A friend was given a Marlin 1895 Guide Gun in 45-70. He does no reloading so I loaded him some cast 350gr at maybe 1200 FPS at the most so he could get used to the rifle and get the sighting close. Next time I saw him he said the loads worked great, only one shot was needed. I asked what did you kill with the rifle? He helps someone with a small herd of buffalo. Every year they cull one to use as meat for their families. My comment was those were practice loads not hunting loads. The range was very close but maybe you really don't need that much of a load to kill just about anything you will find around here.
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